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KMID : 1001020120100020050
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Korean Journal of Urological Oncology
2012 Volume.10 No. 2 p.50 ~ p.55
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Long Term Follow-Up of Medical Treatment in BPH
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Lee Sang-Chul
Jeong Seong-Jin
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Abstract
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The medical treatment in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia(BPH) became an accepted standard of care following the randomized, double-blind, placebo-controlled clinical trials demonstrating that 5?-reductase inhibitor (5ARI) and ?-blocker significantly improved disease specific quality of life and prevents disease progression. Considering the life expectancy, the duration of medical treatment in real life (15-20 years) may be much longer than that of the longest controlled trial (4.5 year). Although the studies on the long-term efficacy and safety of medical therapy showing the favorable outcome have increased considerably, the level of evidence and knowledge on the long-term outcomeare still limited.Further studies and long-term registry data (more than 10 years) are needed in order to investigate thelong-term efficacy and safety of medical treatment in BPH/LUTS.
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KEYWORD
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Lower urinary tract symptoms, Benign prostatic hyperplasia, Medical treatment, Long-term outcome
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